cell surface-binding protein — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T19952	Sulfo-NHS-Biotin	Sulfosuccinimidobiotin,Sulfosuccinimidyl biotin,Biotin-NHS,Sulfo NHS Biotin,N-hydroxysulfosuccinimidyl biotin	Others
	Sulfo-NHS-Biotin (Biotin-NHS) is a water-soluble biotinylation reagent used in Biotin-Streptavidin binding reactions. Sulfo-NHS-Biotin is particularly useful for targeting cell surface proteins in Streptavidin-Biotin ass...
T41068	P53R3		p53
	P53R3 is a potent reactivator of p53, effectively restoring sequence-specific DNA binding to several p53 hot spot mutants, namely p53 R175H, p53 R248W, and p53 R273H. This compound exhibits p53-dependent antiproliferativ...
T34191	Pulchellin	NSC 85244
	Pulchellin is a type-2 Ribosome Inactivating Protein (RIP), whose action mechanism proposed would be initiate by B-chain binding on glycoconjugate onto the cell surface (lectinic chain). pulchellin isoforms toxicity is t...
T71338	Patidegib HCl
	Patidegip, laos known as Saridegib and IPI-926, is an orally bioavailable, cyclopamine-derived (for structure comparison see Fig 1) inhibitor of the Hedgehog (Hh) pathway with potential antineoplastic activity. Specific...
T75116	COVID-19 Spike Protein mRNA-LNP
	COVID-19 Spike Protein mRNA-LNP is a lipid nanoparticle (LNP) formulated with the novel coronavirus pneumonia spike protein, positioned on the membrane surface, designed for applications such as RNA delivery, translation...
T75102	COVID-19 Spike Protein mRNA(N1-Me-Pseudo UTP)
	The COVID-19 Spike Protein mRNA, responsible for expressing the COVID-19 spike protein, is crucial for evaluating RNA delivery, translation efficiency, and cell viability. Positioned on the membrane surface, this spike p...
T37347	6'-Sialyllactose Sodium Salt	6'-Sialyllactose Sodium Salt,6'-N-Acetylneuraminyl-D-lactose
	6'-Sialyllactose consists of the monosaccharide N-acetylneuraminic acid linked to the galactosyl subunit of lactose at the 6 position. This connection is at the 3 position in the related compound, 3’-sialyllactose. Both ...

Recombinant Proteins

Species：

Expression System：

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Cat No.	Product Name	Species	Expression System
TMPK-01252	E8L Protein, Monkeypox virus, Recombinant (His)	Monkeypox virus	E. coli
	E8L is an important protein that mediates the invasion of monkeypox virus into host cells. In the process of invading and completing replication, E8L acts as a surface-binding protein of mature virion and can bind to cho...
TMPJ-00533	LYVE1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 is a single-pass type I membrane protein. LYVE-1 is a CD44 homolog found primarily on lymphatic endothelial cells 1. LYVE-1 mainly expressed in endothelial cells li...
TMPK-01393	Tenascin Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Tenascin-C (TNC) is a hexameric, multimodular extracellular matrix protein with several molecular forms that are created through alternative splicing and protein modifications. It is highly conserved amongst vertebrates,...
TMPK-01392	Tenascin Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Tenascin-C (TNC) is a hexameric, multimodular extracellular matrix protein with several molecular forms that are created through alternative splicing and protein modifications. It is highly conserved amongst vertebrates,...
TMPY-03650	BirA Protein, E. coli, Recombinant (His & MBP)	E. coli	E. coli
	The enzyme BirA is a key reagent because of its ability to biotinylate proteins at a specific residue in a recognition sequence. This enzyme is used to biotinylate the C termini of membrane proteins, allowing these prote...
TMPY-00105	Recombinant Protein G		E. coli
	Protein G is a bacterial cell wall protein expressed at the cell surface of certain group C and group G Streptococcal strains. It has affinity for both Fab- and Fc-fragments of human IgG by independent and separate bindi...
TMPY-00817	Granzyme B/GZMB Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the ...
TMPY-03758	Vaccinia Virus B18R/B19R Protein (His)	VACV	Baculovirus Insect Cells
	B18R is a type I interferon (IFN)-binding protein, which is encoded by the B18R open reading frame in the WR (Western Reserve) strain of vaccinia virus. It is also known as B19R in the Copenhagen strain of Vaccinia. ...
TMPJ-01065	Noggin/NOG Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal pept...
TMPY-04396	C-ABL/ABL1 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cy...
TMPH-02307	Vinculin Protein, Human, Recombinant (GST)	Human	E. coli
	Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play impor...
TMPH-01871	Plastin-2 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69. Plastin-2 Protein, Human, Recom...
TMPJ-00811	IGFBP-1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Insulin-like growth factor-binding protein 1 (IGFBP1) is encoded by 259 amino acid (aa) with 25 aa residue signal peptide that is processed to generate the 234 aa residue mature protein. IGF-binding proteins prolong the ...
TMPH-01872	Plastin-2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69. Plastin-2 Protein, Human, Recom...
TMPJ-01085	DPT Protein, Human, Recombinant (hFc & His)	Human	HEK293 Cells
	Dermatopontin, also known as Tyrosine-rich acidic matrix protein, TRAMP and DPT, is a secreted protein which belongs to the dermatopontin family. DPT is expressed in various tissues, such as fibroblasts, heart, skeletal ...
TMPJ-00563	LGALS3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Galectin-3(LGALS3) is also known as Galactose-specific lectin 3, Mac-2 antigen, Carbohydrate-binding protein 35, Laminin-binding protein and Galactoside-binding protein. LGALS3 is highly expressed in early stages of papi...
TMPH-03315	IGFBP-1 Protein, Rat, Recombinant	Rat	E. coli
	IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surfa...
TMPK-00251	SIRP gamma Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a monomeric 45-47 kDa type I transmembrane protein belonging to the SIRP/SHPS (CD172) family of the Ig superfamily.SIRP gamma i...
TMPH-01447	Human herpesvirus 2 (HHV-2) (strain HG52) Envelope glycoprotein C (His)	HHV-2	E. coli
	Major attachment protein that mediates binding of the virus to cell surface heparan sulfate or chondroitin sulfate. Plays also a role in host immune evasion by inhibiting the host complement cascade activation. Human her...
TMPK-00250	SIRP gamma Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a monomeric 45-47 kDa type I transmembrane protein belonging to the SIRP/SHPS (CD172) family of the Ig superfamily.SIRP gamma i...
TMPH-01048	CEACAM5 Protein, Human, Recombinant (E398K, His)	Human	HEK293 Cells
	Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion mo...
TMPJ-00248	SIRP gamma Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Signal-Regulatory Protein Gamma (SIRPG) is a member of the signal-regulatory protein (SIRP) family and also belongs to the immunoglobulin superfamily. SIRPG is detected in the liver, and at very low levels in the brain, ...
TMPJ-00164	IGFBP-5 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Insulin-Like Growth Factor-Binding Protein 5 (IGFBP-5) is a secreted protein that belongs to the insulin-like growth factor (IGF) binding proteins superfamily. Members of this family prolong the half-life of the IGFs. Th...
TMPH-02277	PTPN11 Protein, Human, Recombinant (T253M & Q257L, His)	Human	E. coli
	Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway. Dephosph...
TMPY-04144	Kremen-1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	KREMEN1 (Kringle Containing Transmembrane Protein 1) is a Protein Coding gene. This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (...
TMPJ-00759	VDB Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Vitamin D-Binding Protein (DBP) is a member of the ALB/AFP/VDB family. DBP is a secreted protein and contains three albumin domains. The primary structure contains 28 cysteine residues forming multiple disulfide bonds. D...
TMPK-00134	ULBP-1 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Cell surface proteins major histocompatibility complex (MHC) class I-related chain A (MICA) and UL16-binding proteins (ULBP) 1, 2, and 3 are up-regulated upon infection or tumor transformation and can activate human natu...
TMPK-00135	ULBP-1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Cell surface proteins major histocompatibility complex (MHC) class I-related chain A (MICA) and UL16-binding proteins (ULBP) 1, 2, and 3 are up-regulated upon infection or tumor transformation and can activate human natu...
TMPH-03587	GspB Protein, S. gordonii, Recombinant (GST)	Streptococcus gordonii	E. coli
	Plays a role in virulence and host-pathogen interactions. Mediates binding to human platelets via interaction with the human cell surface glycoprotein GP1BA. Plays a positive role in biofilm formation, possibly by self-a...
TMPY-06885	SARS-CoV-2 XBB.1.16 (Omicron) Spike S1+S2 trimer Protein (ECD, His)
	The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;...
TMPJ-01176	SEMA4C Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Semaphorin-4C is a protein which belongs to the semaphorin family, contains 1 Ig-like C2-type domain, 1 PSI domain, 1 Sema domain. As cell surface receptor for PLXNB2, it plays an important role in cell-cell signaling. P...
TMPJ-01369	DPT Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Dermatopontin is a widely expressed noncollagenous protein component of the extracellular matrix. It is a 22 kDa molecule that is tyrosine sulfated but not glycosylated. Dermatopontin is down regulated in fibrotic growth...
TMPK-00882	B7-2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti...
TMPH-03574	SdrE Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	E. coli
	Cell surface-associated calcium-binding protein which plays an important role in adhesion and pathogenesis. Contributes to the resistance to killing by innate immune components in blood and thus attenuates bacterial clea...
TMPK-00653	B7-2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti...
TMPH-00213	Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc)	Bothrops atrox	E. coli
	Inhibits fibrinogen interaction with platelets. Acts by binding to the glycoprotein IIb-IIIa receptor (ITGA2B/ITGB3) on the platelet surface and inhibits aggregation induced by ADP, thrombin, platelet-activating factor a...
TMPJ-00426	Siglec-5 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Sialic acid-binding Ig-like lectin 5 is a protein that in Cynomolgus is encoded by the SIGLEC5 gene, Cynomolgus SIGLEC5 cDNA encodes 551 amino acids (aa) that include a 16 aa signal sequence, a 439aa extracellular domai...
TMPK-00880	B7-2 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti...
TMPK-00881	B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti...
TMPH-02529	ASGR2 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine uni...
TMPJ-00270	IL-13RA1 Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293 Cells
	Interleukin-13 receptor subunit alpha-1(IL-13RA1), also known as NR4, belongs to the hemopoietin receptor family. Interleukin-13 receptor is a complex of IL4R, IL13RA1, and possibly other components. It interacts with TR...
TMPY-03977	DAP10 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	HCST (Hematopoietic Cell Signal Transducer, also known as DAP1) is a Protein Coding gene. HCST belongs to the DAP10 family. It is a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. Th...
TMPH-01516	FCGRT Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk. IgG in the milk is bound...
TMPH-03248	ASGR1 Protein, Rat, Recombinant (His & Myc)	Rat	HEK293 Cells
	Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine uni...
TMPY-02592	Annexin VI/ANXA6 Protein, Human, Recombinant (His)	Human	E. coli
	Annexin A6, also known as ANXA6 or ANXAⅥ, belongs to a family of Ca2+-dependent membrane and phospholipid binding proteins. Members of this family have been implicated in membrane-related events along exocytotic and endo...
TMPJ-01312	TWEAKR/TNFRSF12A Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Tumor necrosis factor receptor superfamily member 12A(Tnfrsf12a) is a single-pass type I membrane protein and contains 1 TNFR-Cys repeat. It is weak inducer of apoptosis in some cell types.It promotes angiogenesis and it...
TMPH-01517	FCGRT Protein, Human, Recombinant (GST)	Human	E. coli
	Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk. IgG in the milk is bound...
TMPY-03125	SHP-2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	SHP2, also known as PTPN11, belongs to the protein-tyrosine phosphatase(PTP) family, non-receptor class 2 subfamily. PTPs catalyze the removal of phosphate groups from tyrosine residues by the hydrolysis of phosphoric ac...
TMPJ-00305	SIRP alpha Protein, Cynomolgus, Recombinant (aa 31-369, His)	Cynomolgus	HEK293 Cells
	Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can expre...
TMPY-03847	FRZB Protein, Human, Recombinant (His)	Human	HEK293 Cells
	FRZB also known as sFRP-3, is a secreted protein containing a domain similar to the putative Wnt-binding region of the frizzled family of transmembrane receptors. FRZB is widely expressed in adult mammalian tissues. In t...
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